Hinokiflavone is a SUMO protease inhibitor, inhibiting sentrin-specific protease 1 (SENP1) activity. Hinokiflavone is a novel modulator of pre-mRNA splicing activity in vitro and in cellulo. Hinokiflavone blocks splicing of pre-mRNA substrates by inhibiting spliceosome assembly, specifically preventing B complex formation.
D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
Maltose is a disaccharide formed from two units of glucose joined with an α(1→4) bond, a reducing sugar. Maltose monohydrate can be used as a energy source for bacteria.
(S)-(+)-Carvone (D Carvone) is a naturally occuring conmpound found in several food items and can be used in flavouring foods.
Guanidine thiocyanate is a catalytic solvent. Guanidine thiocyanate is useful as a protein denaturing agent and nucleic acid protectant for DNA and RNA extraction from cells. It inactivates the virus for research.
Polyethylene glycol 8000 (PEG 8000) is a polymer formed by condensation reaction of ethylene oxide and water. Polyethylene glycol is used for the isolation of plasmid DNA and the precipitation of phage.
BMS-986176/LX-9211 is an orally administered, CNS-penetrating AAK1 kinase inhibitor with an IC50 of 2 nM that is being developed for use in neuropathic pain studies.
BMS-986176/LX-9211 is an orally administered, CNS-penetrating AAK1 kinase inhibitor with an IC50 of 2 nM that is being developed for use in neuropathic pain studies.
PY-60 is a specific activator (Kd=1.4 µM) of YAP transcriptional activity targeting membrane associated protein A2 (ANXA2).PY-60 binds directly to ANXA2 and antagonizes its normal cellular function of inhibiting YAP activity.
BMS-986176/LX-9211 is an orally administered, CNS-penetrating AAK1 kinase inhibitor with an IC50 of 2 nM that is being developed for use in neuropathic pain studies.