BI-2865 is a non-covalent pan-KRAS inhibitor that binds to KRAS WT, G12C, G12D, G12V, and G13D mutants with Kd values of 6.9 nM, 4.5 nM, 32 nM, 26 nM, and 4.3 nM, respectively.It can be used in studies related to KRAS mutant tumors.
Mutanocyclin, a tetramic acids analog, is also a potent antifungal agent that inhibits mycelium formation in Candida albicans. In addition, Mutanocyclin also reduces the mRNA expression of HWP1, ECE1, FLO8, TEC1, and has inhibitory activity against immune cell infiltration.
BI-2865 is a non-covalent pan-KRAS inhibitor that binds to KRAS WT, G12C, G12D, G12V, and G13D mutants with Kd values of 6.9 nM, 4.5 nM, 32 nM, 26 nM, and 4.3 nM, respectively.It can be used in studies related to KRAS mutant tumors.
β-Amyrin acetate is a triterpenoid natural product that localizes to HMG CoA reductase and inhibits its activity, with potent anti-inflammatory, anti-fungal, anti-diabetic, and anti-hyperlipidemic activities.
β-Amyrin acetate is a triterpenoid natural product that localizes to HMG CoA reductase and inhibits its activity, with potent anti-inflammatory, anti-fungal, anti-diabetic, and anti-hyperlipidemic activities.
α-Methyl-DL-aspartic acid is a specific inhibitor of argininosuccinate synthase (ASS) and the rate-limiting enzyme of the 1-citrulline to 1-arginine cycle.
α-Methyl-DL-aspartic acid is a specific inhibitor of argininosuccinate synthase (ASS) and the rate-limiting enzyme of the 1-citrulline to 1-arginine cycle.
Ulotaront HCl is a first-in-class, orally active, CNS-active TAAR1 agonist for studies related to schizophrenia.
Ulotaront HCl is a first-in-class, orally active, CNS-active TAAR1 agonist for studies related to schizophrenia.
Angiotensin III, human, mouse is a heptapeptide and an angiotensin type 2 receptor (AT2R) agonist with IC50 values of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.
Angiotensin III, human, mouse is a heptapeptide and an angiotensin type 2 receptor (AT2R) agonist with IC50 values of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.
Felypressin acetate is a non-catecholamine vasoconstrictor and an agonist of vasopressin 1.