Didymin, a dietary flavonoid glycoside from citrus fruits, possesses antioxidant properties. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma.
Ammonium acetate exists as a white crystal. It was prepared from acetic acid and ammonia and neutralized to pH 7.0. It is widely used in analytical chemistry, medicine, textile dyeing and other fields.
2-Iodoacetamide is an alkylating agent that is commonly used to alkylate cysteines during proteomic sample preparation.It can be used to construct animal models of functional dyspepsia.
IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells.
IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells.
Seralutinib (PK10571, GB002) is a novel PDGFR kinase inhibitor with IC50s of 8 nM and 10 nM for PDGFRα and PDGFRβ in enzyme assays, respectively.
Seralutinib (PK10571, GB002) is a novel PDGFR kinase inhibitor with IC50s of 8 nM and 10 nM for PDGFRα and PDGFRβ in enzyme assays, respectively.
Simufilam (PTI-125) Dihydrochloride is a small molecule modulator that preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7nAChR/TLR4 associations and downstream pathologies.
Seralutinib (PK10571, GB002) is a novel PDGFR kinase inhibitor with IC50s of 8 nM and 10 nM for PDGFRα and PDGFRβ in enzyme assays, respectively.
Ensitrelvir (S-217622) is the first oral, non-covalent, non-peptide inhibitor of SARS-CoV-2 3CL (major protease) (IC50=13 nM).
Ensitrelvir (S-217622) is the first oral, non-covalent, non-peptide inhibitor of SARS-CoV-2 3CL (major protease) (IC50=13 nM).
11-Mercaptoundecanoic acid (MUA), a thiol-containing fatty acid used to design monolayers, has been used to prepare self-assembled monolayers (SAMs), hybrid monolayers, and metal-conjugated nanoparticles.