Rimegepant Sulfate is a potent, selective, competitive, orally active calcitonin gene-related peptide (CGRP) antagonist with a Ki of 0.027 nM.May be used in migraine-related studies.
Londamocitinib is a potent and selective JAK1 inhibitor with anti-inflammatory activity.
Londamocitinib is a potent and selective JAK1 inhibitor with anti-inflammatory activity.
2',3'-cGAMP sodium is an endogenous cGAMP in mammalian cells that binds STING with high affinity and is also a potent inducer of interferon-beta (IFNβ).2',3'-cGAMP sodium is produced in mammalian cells in response to DNA in the cytoplasm.
2',3'-cGAMP sodium is an endogenous cGAMP in mammalian cells that binds STING with high affinity and is also a potent inducer of interferon-beta (IFNβ).2',3'-cGAMP sodium is produced in mammalian cells in response to DNA in the cytoplasm.
Terreic acid is a quinone epoxide antibiotic and a potent Btk inhibitor, blocking the interaction between PKC and the PH domain of Btk.T Terreic acid also acts on HMC-1 human mast cell lysates, inhibiting the binding of GST-BtkPH to PKC with an IC50 of approximately 100 μM. Terreic acid also acts on HMC-1 human mast cell lysates to inhibit the binding of...
NLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome-dependent cellular pyroptosis, with an IC50 value of 0.2392 ± 0.0233 μM.
WSP-1 is a selective, fast-reacting H2S-specific fluorescent dye that reacts with H2S and releases fluorophores (Ex/Em=465/515 nm).
Terreic acid is a quinone epoxide antibiotic and a potent Btk inhibitor, blocking the interaction between PKC and the PH domain of Btk.T Terreic acid also acts on HMC-1 human mast cell lysates, inhibiting the binding of GST-BtkPH to PKC with an IC50 of approximately 100 μM. Terreic acid also acts on HMC-1 human mast cell lysates to inhibit the binding of...
Melanotan I is a synthetic analog of α-Melanocyte Stimulating Hormone (α-MSH) and a potent non-selective melanocortin receptor (MCR) agonist that stimulates melanogenesis Melanotan I can be used in studies related to sunlight-induced skin cancer.
Melanotan I is a synthetic analog of α-Melanocyte Stimulating Hormone (α-MSH) and a potent non-selective melanocortin receptor (MCR) agonist that stimulates melanogenesis Melanotan I can be used in studies related to sunlight-induced skin cancer.