Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
Palbociclib Isethionate
Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 2/3.
Enalaprilat Dihydrate
Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.
AM095 free acid
AM095 free acid is a potent LPA1 receptor antagonist which inhibited GTPγS binding to CHO cell membranes overexpressing recombinant human or mouse LPA1 with IC50 values of 0.98 and 0.73 μM, respectively.
Favipiravir
Favipiravir (T-705) is a potent and selective RNA-dependent RNA polymerase inhibitor, used to treat influenza virus infections. Its active form, Favipiravir-ribofuranosyl-5′-triphosphate (RTP) inhibits the influenza viral RNA-dependent RNA polymerase (RdRP) activity with an IC50 of 341 nM.
Tris(2-carboxyethyl)phosphine hydrochloride
Disufide crosslinks of cystines in proteins can be reduced to cysteine residues by TCEP (tris-(2-carboxyethyl)phosphine). Unlike DTT (dithiothreitol), TCEP does not contain thiols and therefore usually does not need to be removed prior to thiol modification.
Vitamin D3
Vitamin D3 (Cholecalciferol) is a form of vitamin D, binds and activates a H305F/H397Y mutant vitamin D receptor (VDR) with EC50 of 300 nM. *The compound is unstable in solutions, freshly prepared is recommended
Casticin (Vitexicarpin)
Casticin (Vitexicarpin) is a methoxyl flavonoid compound obtained from fructus vitae and has anti-mitotic and anti-inflammatory activities. Casticin inhibits the activation of STAT3.
Epoprostenol sodium
Epoprostenol is an endogenous steroid and a selective agonist of the prostaglandin I2 receptor (PI2R) that inhibits platelet aggregation and induces vasodilation. It can be used in studies related to pulmonary hypertension.
AVJ16
AVJ16 is a cancer cell migration inhibitor that targets the insulin-like growth factor 2 mRNA binding protein IGF2BP1 to inhibit the migration of H1299 cells with high endogenous IGF2BP1 expression.
Obeticholic Acid (INT-747)
Obeticholic Acid (INT-747) is a potent, orally active, selective farnesoid X receptor (FXR) agonist with an EC50 of 99 nM.May be used in studies related to non-alcoholic steatohepatitis (NASH).
Lomefloxacin
Lomefloxacin (SC47111A) is a fluoroquinolone antibiotic.
Isoliquiritigenin
Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza glabra, which inhibits aldose reductase with an IC50 of 320 nM.