Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
IACS-13909
IACS-13909 is a potent selective, orally active SHP2 allosteric inhibitor IC50 for 15.7 nM,Kd 32 nM. IACS-13909 is more selective for SHP2 than other phosphatase, including SHP1. IACS-13909 inhibits the signaling of the receptor tyrosine kinase (RTK)/MAPK pathway and has an anticancer effect.
Wu-5
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD degradation and induce apoptosis.
Cyanine5 carboxylic acid chloride
Cyanine5 carboxylic acid chloride is a commonly used fluorescent dye with an emission wavelength around 650 nm that can be used to label proteins.
AZD7507
AZD7507 is a potent, oral CSF-1R inhibitor with antitumor activity.
2'-Fucosyllactose
2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-γ production and decreases IL-6, IL-17, and TNF-α production of cytokines.
Lumefantrine-d9
Lumefantrine-d9
ME0328
ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.
LY3023414
LY3023414 is a selective ATP-competitive inhibitor of PI3Kα and mTOR, DNA-PK, and other class I PI3K family members.
Pempidine
Pempidine is a ganglion-blocking compound.
D-Luciferin
D-Luciferin is a light-emitting compound, also a natural substrate of luciferases.
BMS 794833
BMS-794833 is a potent ATP competitive Met/VEGFR-2 kinase inhibitor.
C16
C16 is a pKR inhibitor.