Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
Maslinic-acid
Maslinic-acid (MA) is a natural triterpenoid with a wide range of biological activities, such as anti-tumor, anti-diabetes, antioxidant, heart-protective, neuroprotective, anti-parasitic and growth stimulating, Maslinic acid inhibited THE DNA binding activity of NF-κB P65 and eliminated the PHOSPHORylation of IκB-α.
Butylhydroxyanisole
Butylhydroxyanisole is an antioxidant, consisting of a mixture of two isomeric organic compounds. Butylhydroxyanisole mediates liver toxicity, retardation in reproductive organ development and learning, and sleep deficit. Butylhydroxyanisole exerts neurotoxic effects and leads to disruption of the brain and nerve development. Butylhydroxyanisole is also a...
HCV-796
HCV-796 is a specific inhibitor of HCV NS5B polymerase with IC50 of 0.01-0.14 μM for genotype 1, with EC50 of 5 nM and 9 nM against genotype 1a and 1b replicons.
A-804598
A-804598 is a CNS penetrant, competitive and selective P2X7 receptor antagonist with IC50s of 9 nM, 10 nM and 11 nM for mouse, rat and human P2X7 receptors, respectively.
Tirapazamine
Tirapazamine (TPZ，SR-4233, WIN 59075) is the first hypoxia-activated prodrug. Tirapazamine kills hypoxic cells by inducing chromosome aberrations and DNA double-strand breaks. Tirapazamine induced cell cycle arrest and apoptosis, and down-regulated HIF-1α, CA-IX and VEGF expression.
Pimonidazole hydrochloride
Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor.
Lixisenatide
Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist, which is a hormone that helps normalize blood sugar levels.
Tideglusib
Tideglusib (NP031112, NP-12) is a potent non ATP-competitive inhibitor of GSK3 with IC50 of 60 nM.
Ripasudil (K-115) dihydrate
Ripasudil (K-115) hydrochloride dihydrate is potent ROCK inhibitor with IC50 of 51 nM and 19 nM for ROCK1 and ROCK2, respectively, used for the treatment of glaucoma and ocular hypertension.
Yunaconitine
Yunaconitine
Selisistat (EX 527)
Selisistat (EX 527) is a potent and selective SIRT1 class III histone deacetylase enzyme inhibitor with an IC50 of 98 nM.
Vancomycin
Vancomycin is a glycopeptide antibiotic as well as a macrocyclic compound that can be used to construct models of bronchiectasis combined with lung infections, as well as for studies related to various bacterial infectious conditions.