Abemaciclib (LY2835219) is a best-in-class, selective and effective dual inhibitor of CDK4 and CDK6, which inhibits CDK4/CDK6 activity with IC50 of 2 nM and 10 nM respectively.
1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate is a lipid that can be used in the synthesis of phospholipid vesicles to improve protein encapsulation.
Kemptide is a synthetic heptapeptide that acts as a specific substrate for camp-dependent protein kinase (PKA).
GSK656 is a potent Mtb LeuRS inhibitor, shows potent inhibition of Mtb LeuRS (IC50 = 0.20 μM) and in vitro antitubercular activity (Mtb H37Rv MIC = 0.08 μM).
TBAJ-587, a potent anti-tuberculosis agent, inhibits M.tb strain H37Rv growth with MIC90s of 0.006 and
Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. Cinchonidine (α-Quinidine) is a weak inhibitor of serotonin transporter (SERT) with Ki values of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively.
Somatostatin is a tetradecapeptide which can suppress the growth hormone (GH) secretion, and regulate the endocrine system to control the pituitary hormone secretion in human CNS.
Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), is used as protein kinase C substrate peptide for testing the protein kinase C activity.