Deltaline is a diterpenoid alkaloid isolated from the genus Delphinium delavayi Franch. Deltaline can be used in pain relief studies, and The Vermilion has also been used in studies of rheumatoid pain, stroke induced paralysis, and rheumatoid arthritis.
Elamipretide TFA, also known as MTP-131, is a cardiolipin peroxidase inhibitor and mitochondria-targeted peptide.
Dorzolamide HCl is a water-soluble inhibitor of human carbonic anhydrase carbonic anhydrase II and IV with a Ki of 1.9 nM and 31 nM, respectively, and can be used in glaucoma-related studies.
DAPI dihydrochloride is A fluorescent dye that binds DNA rich in a-T sequences. The maximum excitation/emission wavelength is 358nm/461 nm, and the blue fluorescence is often used to observe the nucleus and nucleic acid. Store at room temperature away from light.
AZ084 is a potent, selective, allosteric and oral active CCR8 antagonist, with a Ki of 0.9 nM. Has potential to treat asthma.
Camostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.
MSC2530818, a CDK8 inhibitor with the IC50 of 2.6 nM, displays excellent kinase selectivity, biochemical and cellular potency, microsomal stability, and is orally bioavailable.
EED226 is an effective, selective and orally active Polycomb reactive complex 2 (PRC2) inhibitor. When h3k27me0 peptide is used as substrate, ic50=23.4 nm; With mononucleosome as substrate, ic50=53.5 nm. It is a first in class, effective, orally bioavailable inhibitor of embryonic ectodermal development (EED) with strong anticancer effect.
Shanzhiside Methyl ester was isolated from Lactobacillus rotaformis. Shanzhiside Methyl ester, a small molecule glucagon-like peptide 1 (GLP-1 receptor) agonist, has the ability to induce anti-abnormal pain tolerance.
DOTATATE acetate is a DOTA conjugated peptide that can be labeled by radionuclides and used in positron emission tomography (PET) imaging.
D-(+)-Trehalose is used as a food ingredient and pharmaceutical excipient.