Recombinant Mouse Interleukin-17F is produced by Mammalian expression system and the target gene encoding Arg29-Ala161 is expressed with a 6His tag at the C-terminus. Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes.
Recombinant Human Urokinase-Type Plasminogen Activator is a potent marker of invasion and metastasis in many human cancers associated with breast, colon, stomach, bladder, brain, ovary and endometrium.
Avelumab is a whole monoclonal antibody of isotype IgG1 that binds to the programmed death-ligand 1 (PD-L1) and therefore inhibits binding to its receptor programmed cell death 1 (PD-1). Avelumab recognizes murine PD-L1
Recombinant human fibroblast growth factor-10 (FGF-10) is a mitogen produced mainly by lung mesenchymal stem cells. Fgf-10 belongs to the heparin-binding FGF-family, also known as keratinocyte growth factor-2 (KGF-2). It has homology with KGF and receptor with FGFR2-IIIb. Expressed by Escherichia coli.
Neprilysin/CD10 (MME; NEP) is a zinc metallopeptidase expressed at the cell surface of a variety of cells. Neprilysin/CD10 (MME) has been shown to be involved in the degradation of enkephalins in the mammalian brain and the inactivation of circulating atrial natriuretic peptide.
Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST has anti-anabolic effects on bone formation.
Recombinant mouse/rat transforming growth factor β1 is produced by the mammalian expression system and the target gene encoding Ala279-Ser390 is expressed. Measured by its ability to inhibit IL-4-dependent proliferation of TF‑1 human erythroleukemic cells.The ED50 for this effect is 5-25 pg/ml.
Magrolimab (Hu5F9-G4) is a first-in-class humanized anti-CD47 IgG4 antibody with an anti-tumor activity.
Hemoglobin subunit theta-1 is a protein that in humans is encoded by the HBQ1 gene. Hemoglobin has a quaternary structure characteristically composed of many multi-subunit globular proteins. Recombinant Human Hemoglobin Subunit Theta-1 is produced by E.coli expression system and the target gene encoding Met1-Arg142 is expressed with a 6His tag at the...
Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily. Mouse VCAM-1 is Important in cell-cell recognition. it appears to function in leukocyte-endothelial cell adhesion, and interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction.
UBA5 is a member of the ubiquitin activated E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are identified as covalently binding to a variety of cellular substrates through a three-step enzymatic pathway. Ubiquitin activase (E1) plays a crucial role in the first step of activating ubiquitin or ubiquitin-like proteins in the...